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Proteintech
PFN2 Monoclonal Antibody (2H7C12)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
60094-2-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Published species
Human,
Mouse
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
2H7C12
Immunogen
PFN2 Fusion Protein Ag5043 (1-140 aa encoded by BC018049)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.5 mg/mL
Amount
225 µg
Purification
Caprylic acid precipitation
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
The MW of this protein is 15 kDa, and this antibody specifically recognizes the 15 kDa protein.
Immunogen sequence: MAGWQSYVD NLMCDGCCQE AAIVGYCDAK YVWAATAGGV FQSITPIEID MIVGKDREGF FTNGLALGAK KCSVIRDSLY VDGDCTMDIR TKSQGGEPTY NVAVGRAGRV LVFVMGKEGV HGGGLNKKAY SMAKYLRDSG F (1-140 aa encoded by BC018049)
Target Information
Profilin 2 is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: actin binding protein; profilin II; profilin-2-like; unnamed protein product
Gene Aliases: D3S1319E; PFL; Pfn
UniProt ID: (Human) P35080, (Mouse) Q9JJV2, (Rat) Q9EPC6
Entrez Gene ID: (Human) 5217, (Pig) 100621523, (Mouse) 18645, (Rat) 81531
negative regulation of epithelial cell migration
actin cytoskeleton organization
regulation of actin filament polymerization
positive regulation of actin filament polymerization
positive regulation of actin filament bundle assembly
modulation of synaptic transmission
protein stabilization
positive regulation of stress fiber assembly
modification of postsynaptic actin cytoskeleton
presynaptic actin cytoskeleton organization
presynaptic modulation of chemical synaptic transmission
negative regulation of ruffle assembly
negative regulation of actin filament polymerization
regulation of synaptic vesicle exocytosis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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