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          • Primary Antibodies ›
          • PGA5 Antibodies

          Invitrogen

          PGA5 Monoclonal Antibody (2C1)

          View all (16) PGA5 antibodies
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          Cite PGA5 Monoclonal Antibody (2C1)

          • Antibody Testing Data (2)
          PGA5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          PGA5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          PGA5 Antibody (MA5-15558) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded human stomach cancer tissues using PGA5 monoclonal antibody (Product # MA5-15558) followed with DAB staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          PGA5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PGA5 Antibody in Western Blot (WB)

          Product Details

          MA5-15558

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:1,000
          -

          ELISA (ELISA)

          1:10,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Mouse / IgG1

          Class

          Monoclonal

          Type

          Antibody

          Clone

          2C1

          Immunogen

          Purified recombinant fragment of human PGA5 expressed in E. Coli.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          Conc. Not Determined

          Storage buffer

          ascites

          Contains

          0.03% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_10982278

          Product Specific Information

          MA5-15558 targets PGA5 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples.

          The MA5-15558 immunogen is purified recombinant fragment of human PGA5 expressed in E. Coli.

          MA5-15558 detects PGA5 which has a predicted molecular weight of approximately 42kDa.

          Target Information

          PGA5: Pepsinogen 5, group I (pepsinogen A). Pepsinogens are the inactive precursors of pepsin, the major acid protease found in the stomach. Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. PGA5 is a member of the subfamily A1 within the pepsin family and is the predominant endopeptidase in the gastric juice of vertebrates. PGA5 is inhibited by ovUS-1, a uterine serpin.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: pepsin A; Pepsin A-5; Pepsinogen 5; pepsinogen A5; Pepsinogen-5; PGA3; PGA4

          View more View less

          Gene Aliases: Pg5; PGA5

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          UniProt ID: (Human) P0DJD9

          View more View less

          Entrez Gene ID: (Human) 5222

          View more View less

          Function(s)
          aspartic-type endopeptidase activity peptidase activity
          Process(es)
          proteolysis digestion protein catabolic process cellular protein metabolic process
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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