The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
PGC-1 beta is a tissue specific co-activator that enhances the activity of estrogen receptor alpha. The co-activation function relies on a bipartite transcriptional activation domain and two LXXLL motifs that interact with the AR2 domain of ER-alpha in an estrogen-dependent manner. Ectopic expression of this protein has been shown to lead to increased mitochondrial number and basal oxygen consumption.
Protein Aliases: Peroxisome proliferator-activated receptor gamma coactivator 1-beta; peroxisome proliferator-activated receptor gamma, coactivator 1 beta; pgc-1 beta; PGC-1-beta; PGC-1-related estrogen receptor alpha coactivator; PPAR-gamma coactivator 1-beta; PPARgamma coactivator 1 beta; PPARGC-1-beta
Gene Aliases: ERRL1; PERC; PGC-1(beta); PGC1; PGC1B; PPARGC1; PPARGC1B
UniProt ID: (Human) Q86YN6
Entrez Gene ID: (Human) 133522
Molecular Function: transcription cofactor