|Western Blot (WB)||0.5-1 ug/ml|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||An 18 amino acid peptide from near the carboxy terminus of human PGCC1.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
A suggested positive control is rat thymus tissue lysate.
PA5-20801 can be used with blocking peptide PEP-0915.
The transcription factor peroxisome proliferator-activated receptor -gamma (PPARg) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association of various co-factors. One such co-factor, PGCC1 (also known as FAM120B), is widely expressed in adult tissues and throughout embryonic development. Overexpression of this protein in OP9 pre-adipocytes promoted their differentiation into adipocytes, and knockdown of PGCC1 expression through RNA interference blocked this process. PGCC1 is homologous to C9orf10 (also known as FAM120A) and has been mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CCPG, KIAA1838, PGCC1, dJ894D12.1; Constitutive coactivator of peroxisome proliferator-activated receptor gamma; Constitutive coactivator of PPAR-gamma; constitutive coactivator of PPARG; family with sequence similarity 120B; PGCC1; PPARG constitutive coactivator 1; PPARgamma constitutive coactivator 1; Protein FAM120B
Gene Aliases: 4932442K08Rik; AW049283; AW413338; CCPG; dJ894D12.1; FAM120B; KIAA1838; mKIAA1838; PGCC1; RGD1310304
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