|Tested species reactivity||Human, Mouse, Pig, Rat|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues A(176) S S E D T L L K D A A K V C R(191) of human PGP9.5.|
|Storage buffer||whole serum|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||1:2000|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 1 publications below|
PA1-20158 detects PGP9.5 in human, mouse, rat and porcine samples.
PA1-20158 has been successfully used in immunohistochemistry (frozen) and Western blot procedures.
The PA1-20158 immunogen is a synthetic peptide corresponding to residues A(176) S S E D T L L K D A A K V C R(191) of human PGP9.5.
UCHL1 / Protein gene product 9.5(PGP 9.5) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Local insulin and the rapid regrowth of diabetic epidermal axons.
PA1-20158 was used in immunohistochemistry to study the role of insulin deficiency in diabetic polyneuropathy
|Guo G,Kan M,Martinez JA,Zochodne DW||Neurobiology of disease (43:414)||2011|