|Tested species reactivity||Human, Mouse|
|Published species reactivity||Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 3 and 170 of Human PI3 kinase p110 alpha|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (Paraffin) (IHC (P))||See 1 publications below|
PA5-27192 targets PI3 kinase p110 alpha in IHC (P) and WB applications and shows reactivity with Human and mouse samples.
The PA5-27192 immunogen is recombinant protein fragment corresponding to a region within amino acids 3 and 170 of Human PI3 kinase p110 alpha.
Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Snail heterogeneity in clear cell renal cell carcinoma.
PA5-27192 was used in immunohistochemistry - paraffin section to study clear cell renal cell carcinoma and snail heterogeneity
|Zaldumbide L,Erramuzpe A,Guarch R,Pulido R,Cortés JM,López JI||BMC cancer (16:null)||2016|