Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:200 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Recombinant Monoclonal |
Type |
Antibody |
Clone |
ARC2090 |
Immunogen |
A synthesized peptide derived from human PI 3 Kinase R4 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.57 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
Positive Samples: HeLa, Raji, Mouse lung, Mouse brain, Rat brain
Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: phosphatidylinositol 3-kinase-associated p150; Phosphoinositide 3-kinase adaptor protein; Phosphoinositide 3-kinase regulatory subunit 4; phosphoinositide-3-kinase, regulatory subunit 4; phosphoinositide-3-kinase, regulatory subunit 4, p150; PI3-Kinase p150; PI3-kinase p150 subunit; PI3-kinase regulatory subunit 4; PI3-kinase VPS15
Gene Aliases: 2210010O15Rik; C730038E05Rik; C85833; D9Ertd418e; p150; PIK3R4; VPS15
UniProt ID: (Human) Q99570, (Rat) P0C0R5, (Mouse) Q8VD65
Entrez Gene ID: (Human) 30849, (Rat) 363131, (Mouse) 75669
Molecular Function:
kinase modulator
protein-binding activity modulator
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