This antibody is predicted to react with mouse based on sequence homology.
Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Paired-like homeodomain transcription factor-3 (PiTX3) is a member of the homeodomain family of DNA binding proteins. PiTX3 is associated with early ocular development (specifically the developing lens), and has a highly restricted expression pattern in the brain. It is later expressed in other organs and limbs.
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Protein Aliases: Homeobox protein PITX3; MGC12766; paired-like homeodomain 3; Paired-like homeodomain transcription factor 3; Pituitary homeobox 3; PTX3
Gene Aliases: ASMD; ASOD; CTPP4; CTRCT11; PITX3; PTX3
UniProt ID: (Human) O75364
Entrez Gene ID: (Human) 5309