|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide, KLH conjugated, corresponding to an internal domain of human PKD2.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.7|
|Contains||0.01% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-24582 detects Protein Kinase D2 in human samples.
PA1-24582 has been successfully used in immunohistochemistry (FFPE) procedures.
The PA1-24582 immunogen is a synthetic peptide, KLH conjugated, corresponding to an internal domain of human PKD2. Sequence identity/similarity to Mouse: 66/83%.
PKD2, a PKD type protein kinase, contains a N-terminal hydrophobic domain predicted to be a transmembrane region, two cysteine-rich motifs that form zinc finger-like repeats, a pleckstrin homology domain, and a putative kinase domain containing the ATP-binding consensus sequence. PKD2 has been shown to be widely expressed in human tissues. ESTs have been isolated from numerous tissue libraries, including normal breast, spleen, thymus and uterus and cancerous cervix, esophagus, liver and ovary. Caution: The symbol PKD2 is also used for the Polycystic Kidney Disease 2 gene, an ion channel on chromosome 4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.