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Invitrogen
PLA2G2A Recombinant Rabbit Monoclonal Antibody (K01_1Y20)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA563488
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
K01_1Y20
Immunogen
A synthetic peptide of human Secretory phospholipase A2.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.6 mg/mL
Amount
60 µg
Purification
Protein A/G
Storage buffer
50mM tris glycine, pH 7.4, with 40% glycerol, 150mM NaCl, 0.05% BSA
Contains
0.01% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC 3.1.1.4; enhancing factor; eted enzyme type IIA phospholipase A2; GIIC sPLA2; group IIA phospholipase A2; modifier of Min1; non-pancreatic secreted type II phospholipase A2; non-pancreatic secretory phospholipase A2; NPS-PLA2; phosphatidylcholine 2-acylhydrolase 2A; phospholipase A2 precursor (EC 3.1.1.4); phospholipase A2, group IIA (platelets, synovial fluid); PLA2BPLA2; PLA2G2A; PLA2LPLA2S; platelet phospholipase A2; secretory group II phospholipase A2; synovial phospholipase A-2 (EC 3.1.1.4); unnamed protein product
Gene Aliases: EF; MOM1; PLA2; PLA2B; PLA2L; PLA2S; PLAS1; sPLA2; sPla2-IIA
UniProt ID: (Human) P14555, (Rat) P14423, (Mouse) P31482
Entrez Gene ID: (Human) 5320, (Rat) 29692, (Mouse) 18780
phospholipid metabolic process
lipid catabolic process
low-density lipoprotein particle remodeling
intestinal stem cell homeostasis
angiotensin-activated signaling pathway
negative regulation of T cell proliferation
phosphatidylethanolamine metabolic process
phosphatidylcholine metabolic process
phosphatidylglycerol metabolic process
phosphatidic acid metabolic process
arachidonic acid secretion
defense response to Gram-positive bacterium
positive regulation of ERK1 and ERK2 cascade
regulation of neutrophil activation
positive regulation of macrophage derived foam cell differentiation
positive regulation of inflammatory response
positive regulation of cholesterol import
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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