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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human PLK1 (amino acids: 331-508) expressed in E. Coli.|
|Storage buffer||PBS with 0.5% proprietary stabilizer|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:200 - 1:400|
|Immunohistochemistry (IHC)||1:200 - 1:1000|
|Western Blot (WB)||1:500 - 1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-17152 targets PLK1 in FACS, IHC, pep-ELISA, and WB applications and shows reactivity with Human and Mouse samples.
The MA5-17152 immunogen is purified recombinant fragment of human PLK1 (amino acids: 331-508) expressed in E. Coli.
MA5-17152 detects PLK1 which has a predicted molecular weight of approximately 68kDa.
Polo-like kinase 1 (Plk1) plays key roles in many aspects of mitosis. Suppression of Plk1 by p21(Waf1) is responsible for p53-dependent protection against adriamycin-induced caspase-independent mitotic death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
cell cycle regulated protein kinase; PLK-1; polo (Drosophia)-like kinase; polo like kinase; polo-like kinase 1; serine/threonine-protein kinase 13; serine/threonine-protein kinase PLK1
PLK; PLK1; STPK13