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PLK2 Antibody (83431-1-RR) in ICC/IF
Immunofluorescent analysis of (4% PFA) fixed hTERT-RPE1 cells using PLK2 antibody (83431-1-RR, Clone: 230520B2) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG (H+L) (SA00013-2), Acetyl-Tubulin (Lys40) antibody (66200-1-Ig, Clone: 7E5H8, red).
Product Details
83431-1-RR
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
230520B2
Immunogen
PLK2 fusion protein Ag29837
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: SSPAKNFFKK AAAALFGGKK DKARYIDTHN RVSKEDEDIY KLRHDLKKTS ITQQPSKHRT DEELQPPTTT VARSGTPAVE NKQQIGDAIR MIVRGTLGSC SSSSECLEDS TMGSVADTVA RVLRGCLENM PEADCIPKEQ L
Target Information
PLK2 is a serum inducible serine/threonine kinase that is a member of the polo family of serine/threonine kinases which have a role in normal cell division. The kinase may play a role in embryogenesis, wound healing, and neoplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: h PLK-2; hSNK; PLK-2; Polo-like kinase 2; Serine/threonine-protein kinase PLK2; Serine/threonine-protein kinase SNK; Serum-inducible kinase
Gene Aliases: hPlk2; hSNK; PLK2; SNK
UniProt ID: (Human) Q9NYY3
Entrez Gene ID: (Human) 10769
G1/S transition of mitotic cell cycle
protein phosphorylation
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
mitotic spindle organization
mitotic cell cycle checkpoint
Ras protein signal transduction
memory
positive regulation of autophagy
peptidyl-serine phosphorylation
positive regulation of protein binding
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Rap protein signal transduction
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of protein catabolic process
regulation of centriole replication
regulation of synaptic plasticity
long-term synaptic potentiation
long term synaptic depression
negative regulation of dendritic spine development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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