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PLXNB1 Antibody (MA5-24250) in Flow
Flow cytometry of PLXNB1 in Jurkat human acute T cell leukemia cell line. Samples were incubated in PLXNB1 monoclonal antibody (Product # MA5-24250) or isotype control antibody followed by Phycoerythrin-conjugated Anti-Mouse IgG F(ab)2 Secondary Antibody.
Product Details
MA5-24250
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
559830
Immunogen
NS0 mouse myeloma cell line transfected with human Plexin B1
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2610304
Product Specific Information
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Plexin B1 is a protein of the plexin family that in humans is encoded by the PLXNB1gene. Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: plexin 1; plexin 5; plexin-A1; Plexin-B1; Semaphorin receptor SEP
Gene Aliases: KIAA0407; PLEXIN-B1; PLXN5; PLXNB1; SEP
UniProt ID: (Human) O43157
Entrez Gene ID: (Human) 5364
negative regulation of cell adhesion
signal transduction
regulation of cell shape
positive regulation of phosphatidylinositol 3-kinase signaling
cell migration
regulation of cell migration
negative regulation of osteoblast proliferation
intracellular signal transduction
regulation of GTPase activity
positive regulation of GTPase activity
ossification involved in bone maturation
axon extension
neuron projection morphogenesis
positive regulation of axonogenesis
regulation of cytoskeleton organization
semaphorin-plexin signaling pathway
semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis
semaphorin-plexin signaling pathway involved in axon guidance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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