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|Tested species reactivity||Human , Primate|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Human PMP22 cDNA boosted with a 13-amino acid peptide, conjugated to murine IgG.|
|Storage buffer||tris glycine with 150mM NaCl|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:200|
|Western Blot (WB)||Assay-Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Suggested positive control: fetal spinal cord.
Peripheral Myelin Protein 22 (PMP22) is a 160 amino acid glycoprotein which is a member of the claudin family and is thought to play an important role in the structure of peripheral nerve myelin. Irregularities in its gene results in hereditary demyelinating neuropathies. PMP22 protein is present in the compact myelin of adult human peripheral nerve and its distribution mimics that of Myelin Protein zero (P0).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CMT1A, HNPP, CMT1E, GAS-3, HMSNIA, Sp110, DSS
growth arrest-specific protein 3, peripheral myelin protein 22, Peripheral myelin protein 22, PMP-22