For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
This gene is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of this family, DNA directed RNA polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or proteins in vivo.
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Protein Aliases: DNA directed RNA polymerase II polypeptide J-related; DNA-directed RNA polymerase II subunit J2; DNA-directed RNA polymerase II subunit RPB11-b1; polymerase (RNA) II (DNA directed) polypeptide J2; polymerase (RNA) II subunit J2; RNA polymerase II subunit B11-b1
Gene Aliases: HRPB11B; POLR2J2; RPB11b1
UniProt ID: (Human) Q9GZM3
Entrez Gene ID: (Human) 246721