|Tested species reactivity||Dog, Guinea pig, Hamster, Human, Mouse, Non-human primate, Sheep, Pig, Rabbit, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Purified rat liver NADPH-Cytochrome P450 reductase.|
|Storage buffer||PBS with 50% glycerol|
|Contains||0.09% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.5 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-29792 detects POR from mouse, monkey, human, rat, canine, guinea pig, hamster, porcine, rabbit and sheep samples.
PA1-29792 has been successfully used in Western blot applications. Suggested positive controls for this product are rat liver, NADPH, cytochrome, P450 and reductase protein.
The PA1-29792 immunogen is purified rat liver NADPH-Cytochrome P450 reductase.
This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.