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Product Details
CF808729
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:2,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Mouse / IgG1 |
Class |
Monoclonal |
Type |
Antibody |
Clone |
OTI4D12 |
Immunogen |
Human recombinant protein fragment corresponding to amino acids 179-338 of human POU4F3 produced in E.coli. |
Conjugate |
Unconjugated |
Form |
lyophilized |
Concentration |
1 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 8% trehalose |
Contains |
no preservative |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
POU4F3 encodes a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. This protein is found in the retina and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in this gene are the cause of non-syndromic sensorineural deafness autosomal dominant type 15.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Brain-3C; Brain-specific homeobox/POU domain protein 3C; brn-3C; MGC138412; POU domain, class 4, transcription factor 3
Gene Aliases: BRN3C; DFNA15; POU4F3
UniProt ID: (Human) Q15319
Entrez Gene ID: (Human) 5459
transcription from RNA polymerase II promoter
visual perception
sensory perception of sound
vestibulocochlear nerve development
retinal ganglion cell axon guidance
inner ear morphogenesis
auditory receptor cell differentiation
positive regulation of transcription from RNA polymerase II promoter
axon extension
neuromuscular process controlling balance
neuron apoptotic process
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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