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|Tested species reactivity||Chicken, Fruit fly, Human, Mouse, Primate, Pig, Rat|
|Published species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to amino acids at the carboxy terminus of human PP2A catalytic subunit|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:100|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
It is not recommended to aliquot this antibody.
This antibody is not cross-reactive with other PP2A subunits.
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Modulation of AD neuropathology and memory impairments by the isoprostane F2α is mediated by the thromboxane receptor.
PA5-17510 was used in western blot to characterize the behavioral, biochemical, and neuropathologic effects of 8ISO in the triple transgenic mouse model of Alzheimer's disease
|Lauretti E,Di Meco A,Chu J,Praticò D||Neurobiology of aging (36:812)||2015|
PP2A-alpha; protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform; protein phosphatase 2, catalytic subunit, alpha isoform; protein phosphatase 2, catalytic subunit, alpha isozyme; protein phosphatase 2A alpha subunit; protein phosphatase 2A catalytic subunit, alpha isoform; protein phosphatase 2a, catalytic subunit, alpha isoform; protein phosphatase-2A-alpha; replication protein C; serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
PP2A; Pp2a1; PP2Ac; PP2CA; PP2Calpha; PPP2CA; R75353; RCJMB04_3c21; RP-C