This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants.
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Protein Aliases: FLJ36922; FLJ55954; OTTHUMP00000165834; PP-T; PP5; protein phosphatase 5, catalytic subunit; Protein phosphatase T; Serine/threonine-protein phosphatase 5
Gene Aliases: PP5; PPP5; PPP5C; PPT
UniProt ID: (Human) P53041
Molecular Function: protein phosphatase