MA5-15417 targets PPARG in WB applications and shows reactivity with Human samples.
The MA5-15417 immunogen is purified recombinant fragment of PPARG (aa170-270) expressed in E. Coli.
This gene encodes a member of the peroxisome proliferator-activated receptor subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CIMT1; NR1C3; Nuclear receptor subfamily 1 group C member 3; peroxisome proliferator-activated nuclear receptor gamma variant 1; Peroxisome proliferator-activated receptor gamma; PPAR-gamma; PPARG; PPARG1; PPARG2; PPARgamma
Gene Aliases: CIMT1; GLM1; NR1C3; PPARG; PPARG1; PPARG2; PPARgamma
UniProt ID: (Human) P37231
Entrez Gene ID: (Human) 5468