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Product Details
TA504769
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI1B8
Immunogen
Human recombinant protein fragment corresponding to amino acids 42-278 of human PPAT produced in E.coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. This protein is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosynthesis. This gene and PAICS/AIRC, a bifunctional enzyme catalyzing steps six and seven in the purine nucleotide biosynthesis pathway, are located in close proximity on chromosome 4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Amidophosphoribosyltransferase; ATase; EC 2.4.2.14; glutamine phosphoribosylpyrophosphatate amidotransferase; Glutamine phosphoribosylpyrophosphate amidotransferase; glutamine PRPP amidotransferase; GPAT
Gene Aliases: 5730454C12Rik; AA408689; AA675351; AI507113; ATASE; C79945; GPAT; PPAT; PRAT
UniProt ID: (Human) Q06203, (Rat) P35433, (Mouse) Q8CIH9
Entrez Gene ID: (Human) 5471, (Dog) 611407, (Rat) 117544, (Mouse) 231327
G1/S transition of mitotic cell cycle
kidney development
purine nucleotide biosynthetic process
'de novo' IMP biosynthetic process
glutamine catabolic process
lactation
purine nucleobase biosynthetic process
nucleoside metabolic process
purine ribonucleoside monophosphate biosynthetic process
organ regeneration
cellular response to insulin stimulus
cellular response to drug
protein homotetramerization
maternal process involved in female pregnancy
ribose phosphate metabolic process
response to drug
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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