|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 249 of Human PPIE|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27938 targets PPIE in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-27938 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 249 of Human PPIE.
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities and also exhibit RNA-binding activity. Three alternatively spliced transcript variants encoding distinct isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cyclophilin E; Cyclophilin-33; CYP-33; CYP33; Peptidyl-prolyl cis-trans isomerase E; peptidylprolyl isomerase E (cyclophilin E); PPIase E; Rotamase E
Gene Aliases: 2010010D16Rik; CYP-33; CYP33; PPIE
Molecular Function: isomerase
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