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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 1 and 274 of Human PPP1CB|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ChIP assay (ChIP)||Assay-Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28225 targets PPP1CB in IF, IHC (P), ChIP and WB applications and shows reactivity with Human and mouse samples.
The PA5-28225 immunogen is recombinant protein fragment corresponding to a region within amino acids 1 and 274 of Human PPP1CB.
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
beta isoform; catalytic subunit; delta isoform; epididymis secretory sperm binding protein Li 80p; PP-1B; PP1beta; PPP1CD; protein phosphatase 1; protein phosphatase 1, catalytic subunit, beta isoform; protein phosphatase 1, catalytic subunit, beta isozyme; protein phosphatase 1, catalytic subunit, delta isoform; protein phosphatase 1-beta; protein phosphatase 1-delta; serine/threonine protein phosphatase PP1-beta catalytic subunit; serine/threonine-protein; Serine/threonine-protein phosphatase PP1-beta catalytic subunit
1200010B19; HEL-S-80p; PP-1B; PP1B; PP1beta; PPP1CB; PPP1CD