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Product Details
H00005536-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PPP5C (NP_006238.1, 1 a.a. approximately 499 a.a) full-length human protein.
Conjugate
Unconjugated
Form
Liquid
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAMAEGERTE CAEPPRDEPP ADGALKRAEE LKTQANDYFK AKDYENAIKF YSQAIELNPS NAIYYGNRSL AYLRTECYGY ALGDATRAIE LDKKYIKGYY RRAASNMALG KFRAALRDYE TVVKVKPHDK DAKMKYQECN KIVKQKAFER AIAGDEHKRS VVDSLDIESM TIEDEYSGPK LEDGKVTISF MKELMQWYKD QKKLHRKCAY QILVQVKEVL SKLSTLVETT LKETEKITVC GDTHGQFYDL LNIFELNGLP SETNPYIFNG DFVDRGSFSV EVILTLFGFK LLYPDHFHLL RGNHETDNMN QIYGFEGEVK AKYTAQMYEL FSEVFEWLPL AQCINGKVLI MHGGLFSEDG VTLDDIRKIE RNRQPPDSGP MCDLLWSDPQ PQNGRSISKR GVSCQFGPDV TKAFLEENNL DYIIRSHEVK AEGYEVAHGG RCVTVFSAPN YCDQMGNKAS YIHLQGSDLR PQFHQFTAVP HPNVKPMAYA NTLLQLGMM
Target Information
This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ36922; FLJ55954; OTTHUMP00000165834; PP-T; PP5; protein phosphatase 5, catalytic subunit; Protein phosphatase T; Serine/threonine-protein phosphatase 5
Gene Aliases: PP5; PPP5; PPP5C; PPT
UniProt ID: (Human) P53041
Entrez Gene ID: (Human) 5536
G-protein alpha-subunit binding
RNA binding
phosphoprotein phosphatase activity
protein serine/threonine phosphatase activity
signal transducer activity
protein binding
ATP binding
microtubule binding
lipid binding
heat shock protein binding
identical protein binding
ADP binding
metal ion binding
protein phosphatase
MAPK cascade
negative regulation of protein phosphorylation
DNA repair
transcription, DNA-templated
protein dephosphorylation
mitotic nuclear division
response to lead ion
histone dephosphorylation
positive regulation of I-kappaB kinase/NF-kappaB signaling
response to morphine
protein heterooligomerization
cellular response to hydrogen peroxide
cellular response to cadmium ion
negative regulation of neuron death
positive regulation of glucocorticoid receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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