MA5-17157 targets PPY in FACS, pep-ELISA, and WB applications and shows reactivity with Human samples.
The MA5-17157 immunogen is purified recombinant fragment of human PPY (amino acids: 1-95) expressed in E. Coli.
MA5-17157 detects PPY which has a predicted molecular weight of approximately 10.4kDa.
Pancreatic polypeptide (PP) is a 36 amino-acid residue peptide with sequence and 3-D structural homology with NPY and PYY. PP is the least conserved of the three peptides and was the first to be identified. It is almost exclusively expressed in the endocrine pancreas and released in response to cholinergic stimulation and food intake. PP has inhibitory effects on gall bladder secretion, intestinal motility and pancreatic secretion. PP may serve as a marker for certain gut endocrine tumors including carcinoid tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Obinepitide; Pancreatic hormone; Pancreatic icosapeptide; Pancreatic polypeptide; pancreatic polypeptide Y; Pancreatic prohormone; PH; PI; PP; prepro-PP (prepropancreatic polypeptide)
Gene Aliases: PNP; PP; PPY
UniProt ID: (Human) P01298
Entrez Gene ID: (Human) 5539