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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Synthetic peptide made to human PP.|
|Storage buffer||PBS, pH 7.4|
|Contains||15mM sodium azide|
|Storage Conditions||4° C, store in dark|
|Tested Applications||Dilution *|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
ABS 030-06-02 detects PP in human samples.
ABS 030-06-02 has been successfully used in ELISA procedures.
ABS 030-06-02 immunogen is a synthetic peptide made to human PP.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/ml
Pancreatic polypeptide (PP) is a 36 amino-acid residue peptide with sequence and 3-D structural homology with NPY and PYY. PP is the least conserved of the three peptides and was the first to be identified. It is almost exclusively expressed in the endocrine pancreas and released in response to cholinergic stimulation and food intake. PP has inhibitory effects on gall bladder secretion, intestinal motility and pancreatic secretion. PP may serve as a marker for certain gut endocrine tumors including carcinoid tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
IOPPP; pancreatic polypeptide Y; PP1; PPA1; PPase; prepro-PP (prepropancreatic polypeptide); SID6-8061
PNP; PP; PPY