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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Human proteinase PR3 purified leukocyte mass.|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:100-1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Myeloblastin (PR3) is a polymorphonuclear leukocyte serine protease which degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. PR3 plays a role in neutrophil response to inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ACPA; AGP7; azurophil granule protein 7; C-ANCA; C-ANCA antigen; CANCA; Leukocyte proteinase 3; MBN; MBT; Myeloblastin; Neutrophil proteinase 4; NP-4; NP4; P29; PR-3; PR3; serine proteinase, neutrophil; Wegener autoantigen; Wegener granulomatosis autoantigen
ACPA; AGP7; C-ANCA; CANCA; MBN; MBT; NP-4; NP4; P29; PR-3; PR3; PRTN3