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Invitrogen
PRDM9 Recombinant Rabbit Monoclonal Antibody (1H9Z1)
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FIGURE: 1 / 2
PRDM9 Antibody (MA5-51196) in IHC (P)
Immunohistochemistry analysis of PRDM9 in paraffin-embedded human colon carcinoma. Samples were incubated with PRDM9 Recombinant monoclonal antibody (Product # MA5-51196) using a dilution of 1:800 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Product Details
MA5-51196
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
1H9Z1
Immunogen
Recombinant protein (or fragment)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: DSEDSDEEWT PKQQVSPPWV PFRVKHSKQQ KESSRMPFSG ESNVKEGSGI ENLLNTSGSE HVQKPVSSLE EGNTSGQHSG KKLKLRKKNV EVKMYRLRER KGLAYEEVSE PQDDDYLYCE KCQNFFIDSC PNHGPPLFVK DSMVDRGHPN HSVLSLPPGL RISPSGIPEA GLGVWNEASD LPVGLHFGPY EGQITEDEEA ANSGYSWLIT KGRNCYEYVD GQDESQANWM RYVNCARDDE EQNLVAFQYH RKIFYRTCRV IRPGCELLVW YGDEYGQELG IKWG
Target Information
The PR domain is a protein-protein interaction module of about 100 amino acids. PR domain-containing proteins, such as PRDM9, are often involved in transcriptional regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: [histone H3]-lysine36 N-trimethyltransferase PRDM9; [histone H3]-lysine4 N-trimethyltransferase PRDM9; [histone H3]-lysine9 N-trimethyltransferase PRDM9; [histone H4]-lysine20 N-methyltransferase PRDM9; [histone H4]-N-methyl-L-lysine20 N-methyltransferase PRDM9; histone methyl transferase; Histone-lysine N-methyltransferase PRDM9; minisatellite binding protein 3 (115kD); PFM6; PR domain 9; PR domain containing 9; PR domain zinc finger protein 9; PR domain-containing protein 9; Protein-lysine N-methyltransferase PRDM9; unnamed protein product
Gene Aliases: KMT8B; MEISETZ; MSBP3; PFM6; PRDM9; ZNF899
UniProt ID: (Human) Q9NQV7
Entrez Gene ID: (Human) 56979
transcription regulatory region sequence-specific DNA binding
DNA binding
methyltransferase activity
zinc ion binding
recombination hotspot binding
protein-lysine N-methyltransferase activity
transferase activity
histone methyltransferase activity
histone methyltransferase activity (H3-K4 specific)
protein homodimerization activity
sequence-specific DNA binding
metal ion binding
histone methyltransferase activity (H3-K36 specific)
histone H4K20me methyltransferase activity
histone H4K20 monomethyltransferase activity
histone H3K9 trimethyltransferase activity
histone H3K36 trimethyltransferase activity
histone H3K4 trimethyltransferase activity
meiotic gene conversion
chromatin organization
chromatin remodeling
regulation of transcription, DNA-templated
synapsis
female gamete generation
regulation of gene expression
positive regulation of reciprocal meiotic recombination
methylation
reciprocal DNA recombination
negative regulation of apoptotic process
male gamete generation
meiotic cell cycle
meiosis I cell cycle process
positive regulation of fertilization
double-strand break repair involved in meiotic recombination
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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