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PRKD2 (PKD2) is a member of the protein kinase D serine/threonine protein kinase family. PRKD2 is a component in the signal transduction pathway induced by phorbol esters and the CCK b gastrin receptor. It exhibits the strongest homology to the serine threonine protein kinases PKD/PKC and PKCnu, particularly in the duplex zinc finger-like cysteine-rich motif, in the pleckstrin homology domain and in the protein kinase domain. In contrast, it shows only a low degree of sequence similarity to other members of the PKC family.
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Protein Aliases: nPKC-D2; Serine/threonine-protein kinase D2
Gene Aliases: HSPC187; nPKC-D2; PKD2; PRKD2
UniProt ID: (Human) Q9BZL6
Entrez Gene ID: (Human) 25865
Molecular Function: non-receptor serine/threonine protein kinase