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Product Details
H00008575-M02
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
1G12
Immunogen
PRKRA (NP_003681, 101 a.a. approximately 200 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: ANASICFAVP DPLMPDPSKQ PKNQLNPIGS LQELAIHHGW RLPEYTLSQE GGPAHKREYT TICRLESFME TGKGASKKQA KRNAAEKFLA KFSNISPENH
Target Information
PRKRA appears to have a pro-apoptotic function that may be suppressed in the presence of growth factor. It activates EIF2AK2 in the absence of double-stranded RNA (dsRNA).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: interferon-inducible double stranded RNA-dependent protein kinase activator A; Interferon-inducible double-stranded RNA-dependent protein kinase activator A; PKR associated protein X; PKR-associated protein X; PKR-associating protein X; Protein activator of the interferon-induced protein kinase; protein kinase, interferon-inducible double stranded RNA dependent activator; protein kinase, interferon-inducible double stranded RNA-dependent activator; Protein kinase, interferon-inducible double-stranded RNA-dependent activator
Gene Aliases: DYT16; HSD-14; HSD14; PACT; PRKRA; RAX
UniProt ID: (Human) O75569, (Rat) Q4V8C7
Entrez Gene ID: (Human) 8575, (Rat) 311130
protein phosphorylation
positive regulation of cell proliferation
production of siRNA involved in RNA interference
cellular response to oxidative stress
outer ear morphogenesis
middle ear morphogenesis
skeletal system morphogenesis
positive regulation of intrinsic apoptotic signaling pathway
immune response
negative regulation of cell proliferation
response to virus
gene silencing by RNA
pre-miRNA processing
production of miRNAs involved in gene silencing by miRNA
positive regulation of catalytic activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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