This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated. View Details
MA5-15796 targets CARM1 in FACS, IF, IHC, and WB applications and shows reactivity with Human, Non-human primate, Mouse and Rat samples.
The MA5-15796 immunogen is purified recombinant fragment of human CARM1 expressed in E. Coli.
MA5-15796 detects CARM1 which has a predicted molecular weight of approximately 65kDa.
Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in DNA packaging, transcription regulation, signal transduction, mRNA stability, metabolism of nascent pre-RNA, and transcriptional activation. Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Coactivator-associated arginine methyltransferase 1; coactivator-associated arginine methyltransferase 1 variant 5; Histone-arginine methyltransferase CARM1; protein arginine methyltransferase; Protein arginine N-methyltransferase 4
Gene Aliases: CARM1; PRMT4