|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptides corresponding to residues M(1) V E L M F P(7) and L(312) L G L P I D(318) of human PSDR1.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-4231 detects the PSDR1 protein in human samples.
PA1- 4231 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~28 kDa protein representing PSDR1 in androgen-stimulated metastatic adenocarcinoma LNCaP.FGC cells.
PA1- 4231 immunogen is a mixture of synthetic peptides corresponding to the N- and C-terminal residues M(1) V E L M F P(7) and L(312) L G L P I D(318) of human PSDR1.
PSDR1 is a novel prostate short-chain dehydrogenase/reductase that exhibits increased expression on exposure to androgens in the LNCaP prostate cancer cell line. PSDR1 is expressed in normal and neoplastic prostate epithelium and is implicated in the pathogenesis of prostate carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.