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Product Details
MA5-30795
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
002
Immunogen
Recombinant Human PSG1/PS-beta-G-1 Protein (Met1-Pro419)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2786477
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human PSG1/PS-beta-G-1.
Target Information
Human pregnancy-specific glycoproteins (PSG), are a group of closely related secreted glycoproteins which are highly expressed in placental syncytiotrophoblast cells of fetal origin. PSG are commonly expressed in tumors of trophoblast origin (hydatidiform mole, choriocarcinoma). They represent the most abundant fetal protein in the maternal blood at term. The eleven human PSG genes (PSG1-PSG11) form together with the carcinoembryonic antigen (CEA)-related cell adhesion molecule (CEACAM) genes the CEACAM gene family. PSG stimulates secretion of TH2-type cytokines from monocytes. CD9 was shown to represent the monocyte receptor for murine PSG17. PSG are thought to modulate the maternal immune system during pregnancy thus protecting the semiallotypic fetus from rejection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD66 antigen-like family member F; CD66f; Fetal liver non-specific cross-reactive antigen 1/2; FL-NCA-1/2; FLJ90598; FLJ90654; pregnancy-specific B-1 glycoprotein; Pregnancy-specific beta-1 glycoprotein C/D; Pregnancy-specific beta-1-glycoprotein 1; PS-beta-C/D; PS-beta-G-1; PSG 1; PSG IIA-d; PSG-1d; PSG95; PSGIIA-a; PSGIIA-b; PSGIIA-c; SP 1
Gene Aliases: B1G1; CD66f; DHFRP2; FL-NCA-1/2; PBG1; PS-beta-C/D; PS-beta-G-1; PSBG-1; PSBG1; PSG1; PSG95; PSGGA; PSGIIA; SP1
UniProt ID: (Human) P11464
Entrez Gene ID: (Human) 5669
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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