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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Mouse / IgG|
|Immunogen||Recombinant human EP2 and EP3 receptor protein.|
|Contains||0.08% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1 - 5 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A suggested positive control for this product is porcine brain lysate.
Prostaglandins (PG's) are produced by the metabolism of arachidonic acid. PGE-2 is one of the five physiologically significant prostanoids known. It"e;s wide spectrum of physiologic and pharmacologic effects in various tissues are mediated through binding to the PGE-2 receptors (EP1, EP2, EP3 & EP4). These include effects on the immune, endocrine, cardiovascular, renal and reproductive systems as well as smooth muscle. It is also one of the most abundant of the prostanoid family in the brain where it plays an important role in many neural functions, particularly in newborn babies, and as a mediator of inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
EP2 receptor; PGE receptor EP2 subtype; PGE receptor EP3 subtype; PGE receptor, EP2 subtype; PGE receptor, EP3 subtype; PGE2 receptor EP2 subtype; PGE2 receptor EP3 subtype; prostaglandin E receotor EP3 subtype 3 isoform; prostaglandin E receptor 2 (EP2 subtype); prostaglandin E receptor 2 (subtype EP2), 53kD; prostaglandin E receptor 2 (subtype EP2), 53kDa; prostaglandin E receptor 3 (subtype EP3); prostaglandin E receptor EP2 subtype; prostaglandin E receptor EP3 subtype; prostaglandin E receptor subtype EP2; Prostaglandin E2 Receptor EP2 + EP3; prostaglandin E2 receptor EP2 subtype; prostaglandin E2 receptor EP3 subtype; prostaglandin E2 receptor type 2; prostaglandin receptor (PGE-2); prostanoid EP2 receptor; prostanoid EP3 receptor; PTGER2; PTGER3
EP2; EP3; EP3-I; EP3-II; EP3-III; EP3-IV; EP3-VI; EP3e; PGE2-R; Pgerep3; Ptger-ep2; PTGER2; PTGER3; Ptgerep2; Ptgerep3; Rep3; rEP3a; rEP3b