|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 20 amino acid peptide from 1st extracellular domain of human PTH2R / PTHR2.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||9 µg/ml|
Percent identity with other species by BLAST analysis: Human (100%) Gorilla, Gibbon, Monkey (95%).
PTHR2 is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by g proteins which activate adenylyl cyclase. PTHR2 may be responsible for PTH effects in a number of physiological systems, and may also play a significant role in pancreatic function. PTHR2 presence in neurons indicates that it may function as a neurotransmitter receptor.