This gene encodes twinfilin, an actin monomer-binding protein conserved from yeast to mammals. Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein, and its localization to cortical G-actin-rich structures may be regulated by the small GTPase RAC1.
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Protein Aliases: A6; A6 protein tyrosine kinase; Protein A6; Protein tyrosine kinase 9; PTK9; PTK9 protein tyrosine kinase 9; twinfilin actin-binding protein 1; twinfilin, actin-binding protein, homolog 1; Twinfilin-1
Gene Aliases: A6; PTK9; TWF1
UniProt ID: (Human) Q12792
Entrez Gene ID: (Human) 5756