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Search Thermo Fisher Scientific
Immunogen sequence: NAVYDVVEE KLENEPDFQY IPEKAPLDSV HQDDHSLRES MIQLAEGLIT GTVLTQFDQL YRKKPGMTMS CAKLPQNISK NRYRDISPYD ATRVILKGNE DYINANYINM EIPSSSIINQ YIACQGPLPH TCTDFWQMTW EQGSSMVVML TTQVERGRVK CHQYWPEPTG SSSYGCYQVT CHSEEGNTAY IFRKMTLFNQ EKNESRPLTQ IQYIAWPDHG VPDDSSDFLD FVCHVRNKRA GKEEPVVVHC SAGIGRTGVL ITMETAMCLI ECNQPVYPLD IVRTMRDQRA MMIQTPSQYR FVCEAILKVY EEGFVKPLTT STNK
The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signaling downstream of the glutamate receptors through tyrosine dephosphorylation.
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Protein Aliases: MEG; megakaryocyte phosphatase; megakaryocyte protein-tyrosine phosphatase; protein tyrosine phosphatase MEG1; protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte); Protein-tyrosine phosphatase MEG1; PTP PTPMEG1; PTPase-MEG1; Tyrosine-protein phosphatase non-receptor type 4
Gene Aliases: MEG; PTPMEG; PTPMEG1; PTPN4
UniProt ID: (Human) P29074
Entrez Gene ID: (Pig) 100522902, (Human) 5775, (Rat) 246116
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