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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:1,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Between 100 and 150 |
Conjugate |
Unconjugated |
Form |
liquid |
Concentration |
40 µg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
TBS with 0.1% BSA |
Contains |
0.09% sodium azide |
Storage conditions |
4° C |
The recommended shelf life for this product is 1 year from date of receipt.
Pseudouridylate synthase that catalyzes pseudouridylation of RNAs (PubMed:28073919, PubMed:29628141, PubMed:30778726). Acts as a regulator of protein synthesis in embryonic stem cells by mediating pseudouridylation of RNA fragments derived from tRNAs (tRFs): pseudouridylated tRFs inhibit translation by targeting the translation initiation complex (PubMed:29628141). Also catalyzes pseudouridylation of mRNAs: mediates pseudouridylation of mRNAs with the consensus sequence 5'-UGUAG-3' (PubMed:28073919). In addition to mRNAs and tRNAs, binds other types of RNAs, such as snRNAs, Y RNAs and vault RNAs, suggesting that it can catalyze pseudouridylation of many RNA types (PubMed:29628141). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ20485; Pseudouridylate synthase 7 homolog
Gene Aliases: KIAA1897; PUS7
UniProt ID: (Human) Q96PZ0
Entrez Gene ID: (Human) 54517
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