This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternate splicing results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ARCL2B; ARCL3B; mitochondrial; mitochondrial pyrroline-5-carboxylate reductase 1; P5C; P5C reductase 1; P5CR; P5CR 1; PIG45; PP222; PRO3; proliferation-inducing protein 45; PYCR; pyrroline-5-carboxylate reductase 1; Pyrroline-5-carboxylate reductase 1, mitochondrial
Gene Aliases: ARCL2B; ARCL3B; P5C; P5CR; PIG45; PP222; PRO3; PYCR; PYCR1
UniProt ID: (Human) P32322
Entrez Gene ID: (Human) 5831