ABS 029-01-02 detects PYY in human samples.
ABS 029-01-02 has been successfully used in ELISA and immunohistochemistry procedures.
ABS 029-01-02 immunogen is a synthetic peptide made to human PYY.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
Peptide tyrosine-tyrosine amide (3-36), or PYY (3-36), is a major metabolite of the gut hormone PYY and is produced by the action of dipeptidyl peptidase IV on PYY in the intestinal brush border and in the circulation. PYY (3-36) is a potent inhibitor of food intake in rats and humans, acting selectively on the Y2 receptor to inhibit orexigenic NPY neurons in the arcuate nucleus, thus disinhibiting anorexigenic POMC neurons. The anorexigenic effect of PYY (3-36) is additive to that of the co-secreted gut hormone GLP-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Peptide tyrosine tyrosine; Peptide YY; Peptide YY(3-36); Peptide YY3-37; prepro-PYY; PYY; PYY-I; PYY-II
Gene Aliases: PYY; PYY-I; PYY1
UniProt ID: (Human) P10082
Entrez Gene ID: (Human) 5697