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Antibodies Inc
Pan-KChIP K+ Channel Monoclonal Antibody (K55/82), FL650
Product Details
75-006-FL650
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
K55/82
Immunogen
Fusion protein amino acids 1-216 (full length) of rat KChIP1b (accession number Q8R426) produced recombinantly in E. Coli.
Conjugate
Excitation/Emission Max
655/676 nm
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
Pan-KChIP refers to the collective group of Kv Channel-Interacting Proteins (KChIPs), which are auxiliary subunits that associate with voltage-gated potassium (Kv) channels. These proteins modulate the trafficking, surface expression, and functional properties of Kv channels, thereby influencing neuronal excitability and signaling. Dysregulation of KChIPs has been implicated in various neurological conditions, including epilepsy and ataxia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A-type potassium channel modulating protein 3; A-type potassium channel modulatory protein 1; A-type potassium channel modulatory protein 1.2; A-type potassium channel modulatory protein 2; A-type potassium channel modulatory protein 3; A-type potassium channel modulatory protein 4; A-type potassium channel modulatory protein KCNIP1; A-type potassium channel modulatory protein KCNIP2; Calsenilin; calsenilin presenilin-binding protein EF hand transcription factor; calsenilin, presenilin binding protein, EF hand transcription factor; calsenilin, presenilin-binding protein, EF hand transcription fa; calsenilin, presenilin-binding protein, EF hand transcription factor; Calsenilin-like protein; Cardiac voltage-gated potassium channel modulatory subunit; downstream regulatory element-antagonist modulator; DRE-antagonist modulator; DREAM; KChIP1; KChIP2; KChIP3; KChIP4; Kv channel interacting protein 1; Kv channel interacting protein 2; Kv channel interacting protein 3; Kv channel interacting protein 3, calsenilin; Kv channel interacting protein 4; Kv channel-interacting protein 1; Kv channel-interacting protein 2; Kv channel-interacting protein 3; Kv channel-interacting protein 4; potassium channel auxiliary subunit KCHIP2; potassium channel interacting protein 1; potassium channel interacting protein 3; potassium channel interacting protein 4; Potassium channel-interacting protein 1; Potassium channel-interacting protein 2; Potassium channel-interacting protein 4; Vesicle APC-binding protein
Gene Aliases: 4933407H12Rik; AI413860; AV032399; CALP; Calp250; CSEN; DREAM; KCHIP1; Kchip1.2; KCHIP2; KCHIP3; KCHIP4; KChIP4a; KCNIP1; KCNIP2; KCNIP3; KCNIP4; R74849; rKChIP3; VABP
UniProt ID: (Human) Q9NZI2, (Human) Q9NS61, (Human) Q9Y2W7, (Human) Q6PIL6, (Mouse) Q9JJ57, (Rat) Q8R426, (Mouse) Q9JJ69, (Rat) Q9JM59, (Mouse) Q9QXT8, (Rat) Q9JM47, (Rat) Q99MG9, (Mouse) Q6PHZ8
Entrez Gene ID: (Human) 30820, (Human) 30819, (Human) 30818, (Human) 80333, (Mouse) 70357, (Rat) 65023, (Mouse) 80906, (Rat) 56817, (Mouse) 56461, (Rat) 65199, (Rat) 259243, (Mouse) 80334
voltage-gated ion channel activity
potassium channel activity
calcium ion binding
protein binding
potassium channel regulator activity
A-type (transient outward) potassium channel activity
ion channel binding
ER retention sequence binding
protein N-terminus binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription corepressor activity
metal ion binding
protein heterodimerization activity
identical protein binding
protein C-terminus binding
sequence-specific DNA binding
calcium-dependent protein binding
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
transport
ion transport
potassium ion transport
intracellular protein transport
apoptotic process
sensory perception of pain
regulation of ion transmembrane transport
regulation of neuron apoptotic process
negative regulation of transcription, DNA-templated
response to pain
behavioral response to pain
potassium ion transmembrane transport
protein localization to plasma membrane
regulation of potassium ion transmembrane transport
cardiac conduction
clustering of voltage-gated potassium channels
potassium ion export
membrane repolarization
protein heterooligomerization
detection of calcium ion
muscle contraction
signal transduction
chemical synaptic transmission
regulation of heart contraction
regulation of cation channel activity
positive regulation of action potential
biological_process
regulation of transcription from RNA polymerase II promoter
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