|Tested species reactivity||Virus|
|Published species reactivity||Not Applicable|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Paramyxovirus SV5, Simian-Virus 5|
|Contains||0.09% sodium azide|
|Storage Conditions||4°C or -20°C if preferred|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||Assay dependent|
|Immunofluorescence (IF)||Assay dependent|
|Immunohistochemistry (Frozen) (IHC (F))||Assay dependent|
|Immunoprecipitation (IP)||Assay dependent|
|Radioimmune Assays (RIA)||Assay dependent|
|Western Blot (WB)||1:1000-1:5000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 1 publications below|
MA1-34099 detects Paramyxovirus SV5 Pk from virus samples.
MA1-34099 has been successfully used in ELISA, immunocytochemistry, immunofluorescence, immunohistochemistry (frozen tissue), immunoprecipitation, radioimmune assay, and Western blot applications.
The MA1-34099 immunogen is paramyxovirus SV5, Simian-Virus 5
The paramyxovirus family includes many well known human and animal pathogens as well as emerging viruses such as Hendra virus and Nipah virus. The V protein of simian virus 5 (SV5), a prototype of the paramyxoviruses, contains a cysteine-rich C-terminal domain which is conserved among all paramyxovirus V proteins. The V protein can block both interferon (IFN) signaling by causing degradation of STAT1 and IFN production by blocking IRF-3 nuclear import.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
Welander distal myopathy is caused by a mutation in the RNA-binding protein TIA1.
MA1-34099 was used in immunohistochemistry to study the causative role of TIA RNA-binding protein mutation in Welander distal myopathy.
|Hackman P,Sarparanta J,Lehtinen S,Vihola A,Evilä A,Jonson PH,Luque H,Kere J,Screen M,Chinnery PF,Åhlberg G,Edström L,Udd B||Annals of neurology (73:500)||2013|