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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit|
|Immunogen||A synthetic peptide from aa region 180-220 of human Pejvakin conjugated to an immunogenic carrier protein was used as the antigen|
|Storage buffer||whole serum|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (IHC)||1:300 - 1:2000|
|Western Blot (WB)||1:300 - 1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Glycerol (1:1) may be added for additional stability.
Reconstitute in 100ul of distilled water.
Essential in the activity of auditory pathway neurons. Defects in PJVK are the cause of non-syndromic sensorineural deafness autosomal recessive type 59 (DFNB59). DFNB59 is a form of sensorineural hearing impairment with absent or severely abnormal auditory brainstem response but normal otoacoustic emissions (auditory neuropathy or auditory dys-synchrony). Auditory neuropathies result from a lesion in the area including the inner hair cells, connections between the inner hair cells and the cochlear branch of the auditory nerve, the auditory nerve itself and auditory pathways of the brainstem. 'Pejvak' means 'echo' in Persian.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
autosomal recessive 59; autosomal recessive deafness type 59 protein; autosomal recessive deafness type 59 protein homolog; DFNB59; DFNB59 deafness; pejvakin; PJVK
DFNB59; Gm1001; PJVK