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GenScript
Pembrolizumab Recombinant Rabbit Monoclonal Antibody (90G12), Biotin, MonoRab™
FIGURE: 1 / 3
Pembrolizumab Antibody (A01853-40) in ELISA
MonoRab™ Anti-Pembrolizumab antibody (90G12) (GenScript, A01853-40) blocks Pembrolizumab binding with Human PD-1 recombinant protein (Z03370, PD 1-Fc Chimera, Human). Coating antigen: Pembrolizumab, 1 µg/mL. PD 1-Fc-biotin final concentration: 20 ng/mL. Anti-Pembrolizumab antibody (GenScript, A01853-40) dilution start from 10 µg/mL. IC50 = 0.38 µg/mL.
Product Details
A01853-40
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
Mammalian cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
90G12
Immunogen
Pembrolizumab
Conjugate
Form
Lyophilized
Purification
Protein A
Storage buffer
PBS, pH 7.4, with BSA
Contains
0.02% sodium azide
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
Pembrolizumab(Keytruda) is a humanized monoclonal antibody that is approved by the U.S. Foodand Drug Administration for the treatment of patients with unresectable ormetastatic melanoma. Pembrolizumab binds to the human cell surface receptorPD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1,resulting in the activation of T-cell-mediated immune responses against tumorcells.GenScript MonoRab™ Anti-PembrolizumabAntibody (90G12F8) [Biotin], mAb, Rabbit is produced from ahybridoma resulting from the fusion of partner and B-lymphocytes obtained froma rabbit immunized with Pembrolizumab.
Target Information
Pembrolizumab (Keytruda) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Pembrolizumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Keytruda; MK-3475
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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