Antigen Affinity Purified from Pooled Serum
AKT also known as protein kinase B (PKB) or RAS-alpha, is an ubiquitous serine/threonine kinase that plays an important role in diverse biological responses such as regulation of metabolism, cell survival and growth by phosphorylating multiple proteins. This protein kinase is activated by insulin, PI3K, IGF1 and various other growth and survival factors. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including forkhead transcription factors, and caspase-9. The AKT pathway is a major target for cancer drug discovery.
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Protein Aliases: Akt; Akt kinase; Akt1; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; DAkt; dAkt kinase; PKB; Protein kinase B; RAC serine/threonine-protein kinase; related to PKA to PKC protein kinases; related to the A and C kinases
Gene Aliases: AKT; AKT/PKB; AKT1; Akt1|PKB; CG4006; D-Akt; DAkt; dAKT/dPKB; dAkt/PKB; DAKT1; DAKT1/PKB; Dmel\CG4006; Dmel_CG4006; DPKB; DRAC-PK; DRAC-PK66; DRAC-PK85; l(3)04226; l(3)89Bq; p-Akt; pAkt; PKB; PKB/AKT; PKB/dAKT; RAC; RacPK
UniProt ID: (Fruit fly) Q8INB9
Entrez Gene ID: (Fruit fly) 41957
Molecular Function: annexin calcium-binding protein calmodulin intracellular calcium-sensing protein kinase non-receptor serine/threonine protein kinase protein kinase transfer/carrier protein transferase