Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
AS160 domain family member 4], is a 160 kDa protein expressed in many tissues including brain, kidney, and liver. The protein is a Rab GTPase activating protein (GAP) involved in control of energy functions such as glucose and lipid metabolism. In humans, the gene is located on the q arm of chromosome 13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Acrg embryonic lethality minimal region ortholog; Akt substrate of 160 kDa; AS160; BUB2; CDC16) domain-containing protein; TBC (Tre-2; TBC (Tre-2, BUB2, CDC16) domain-containing protein; TBC1 domain family member 4; TBC1 domain family, member 4
Gene Aliases: AS160; KIAA0603; NIDDM5; TBC1D4
UniProt ID: (Human) O60343
Entrez Gene ID: (Human) 9882