|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||A synthetic peptide with a phosphorylated serine (1981).|
|Storage buffer||tris glycine with 0.15M NaCl|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:200|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody does not react with canine samples.
Suggested positive control: Irradiated normal human fibroblasts.
No reactivity against un-irradiated cell extracts.
ATM-kinase plays an important regulatory role. DNA damage caused by such things as ionizing irradiation activates ATM-kinase, leading to a cascade of kinase reactions that regulate cell cycle, apoptosis, and DNA damage repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.