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7TM Antibodies
Phospho-Atypical Chemokine Receptor 3 (Ser350, Thr352) Polyclonal Antibody
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FIGURE: 1 / 2
Phospho-Atypical Chemokine Receptor 3 (Ser350, Thr352) Antibody (7TM0080A) in WB
Agonist-induced Serine350/Threonine352 phosphorylation of the Atypical Chemokine Receptor 3/CXC Chemokine Receptor 7. Upper panel, HEK293 cells stably expressing the Atypical Chemokine Receptor 3/CXC Chemokine Receptor 7 (ACKR3/CXCR7) were either not exposed or exposed to 100 nM CXCL12 or 0. 1 µM PMA (Phorbol 12-Myristate 13-Acetate) for 30 minutes. Cells were lysed and immunoblotted with the anti-pS350/pT3... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
7TM0080A
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic phosphopeptide derived from human ACKR3 around the phosphorylation site of Ser350/Thr352.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
Dulbecco's PBS, pH 7.4
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C Cmotif chemokine; C X C motif chemokine; C-X-C chemokine receptor type 7; CC motif chemokine; CCmotif chemokine; chemokine; chemokine (C-X-C motif) receptor 7; chemokine orphan receptor 1; CXC; CXC motif chemokine; G protein-coupled receptor; G-protein coupled receptor 159; G-protein coupled receptor RDC1 homolog; unnamed protein product
Gene Aliases: CMKOR1; CXC-R7; CXCR-7; CXCR7; GPR159; RDC-1; RDC1
UniProt ID: (Human) P25106, (Mouse) P56485
Entrez Gene ID: (Human) 57007, (Mouse) 12778
angiogenesis
vasculogenesis
chemotaxis
immune response
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
negative regulation of cell proliferation
calcium-mediated signaling
oculomotor nerve development
receptor internalization
cell chemotaxis
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of mesenchymal stem cell migration
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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