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Invitrogen

Phospho-CDK1/CDK2 (Thr14) Recombinant Rabbit Monoclonal Antibody (19D6)

View all (8) CDK1/CDK2 antibodies

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Product Details

MA572481

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:500
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunoprecipitation (IP)

1:20-1:50
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

19D6

Immunogen

KLH conjugated synthetic peptide derived from human CDK1 around the phosphorylation site of T14.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.8 mg/mL

Amount

80 µg

Purification

Protein A

Storage buffer

TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: cdc2-related protein kinase; CDK2; cell cycle controller CDC2; cell cycle p34 CDC2 kinase protein; cell division control protein 2 homolog; cell division cycle 2 homolog A; cell division cycle 2, G1 to S and G2 to M; Cell division cycle control protein 2; cell division cycle control protein 2a; cell division protein kinase 1; cell division protein kinase 2; cyclin dependent kinase 2-alpha; p33 protein kinase; p34 protein kinase; unnamed protein product

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Gene Aliases: A630093N05Rik; CDC2; CDC28A; Cdc2a; CDKN2; p33(CDK2); p34; P34CDC2

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UniProt ID: (Human) P06493, (Human) P24941, (Mouse) P11440, (Rat) P39951, (Mouse) P97377

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Entrez Gene ID: (Human) 983, (Human) 1017, (Mouse) 12534, (Rat) 54237, (Rat) 362817, (Mouse) 12566

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Function(s)
chromatin binding protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding RNA polymerase II carboxy-terminal domain kinase activity kinase activity cyclin binding Hsp70 protein binding histone kinase activity cyclin-dependent protein kinase activity protein serine kinase activity magnesium ion binding protein domain specific binding macromolecular complex binding
Process(es)
G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle microtubule cytoskeleton organization DNA replication DNA repair chromatin remodeling regulation of transcription from RNA polymerase II promoter cellular response to DNA damage stimulus mitotic nuclear envelope disassembly mitotic G2 DNA damage checkpoint centrosome cycle pronuclear fusion response to toxic substance positive regulation of gene expression positive regulation of G2/M transition of mitotic cell cycle regulation of Schwann cell differentiation response to amine response to activity cell migration protein deubiquitination peptidyl-threonine phosphorylation chromosome condensation epithelial cell differentiation negative regulation of protein ubiquitination protein localization to kinetochore positive regulation of protein import into nucleus response to hydrogen peroxide regulation of circadian rhythm negative regulation of apoptotic process response to ethanol positive regulation of DNA replication positive regulation of smoothened signaling pathway regulation of embryonic development response to cadmium ion response to copper ion response to axon injury ventricular cardiac muscle cell development positive regulation of cardiac muscle cell proliferation positive regulation of mitotic sister chromatid segregation protein-containing complex assembly cellular response to hydrogen peroxide ERK1 and ERK2 cascade Golgi disassembly regulation of heterochromatin organization positive regulation of protein localization to nucleus regulation of mitotic attachment of spindle microtubules to kinetochore microtubule cytoskeleton organization involved in mitosis positive regulation of mitochondrial ATP synthesis coupled electron transport positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process protein phosphorylation nuclear envelope organization cell proliferation negative regulation of gene expression peptidyl-serine phosphorylation mitotic cell cycle phase transition thymidine biosynthetic process microtubule polymerization cilium disassembly DNA strand resection involved in replication fork processing DNA synthesis involved in mitotic DNA replication protein localization to site of double-strand break mitotic DNA-dependent DNA replication negative regulation of transcription from RNA polymerase II promoter lens development in camera-type eye potassium ion transport centriole replication signal transduction Ras protein signal transduction positive regulation of cell proliferation response to xenobiotic stimulus positive regulation of heterochromatin assembly positive regulation of DNA-dependent DNA replication initiation response to estradiol cellular response to insulin stimulus negative regulation of protein catabolic process telomere maintenance in response to DNA damage post-translational protein modification positive regulation of transcription, DNA-templated response to cAMP response to electrical stimulus liver regeneration negative regulation of protein localization to chromatin positive regulation of meiotic cell cycle process involved in oocyte maturation meiotic spindle organization meiotic cell cycle process involved in oocyte maturation regulation of mitotic cell cycle mitotic G1 DNA damage checkpoint centrosome duplication meiotic cell cycle cellular response to nitric oxide cellular senescence regulation of anaphase-promoting complex-dependent catabolic process telomere maintenance protection from non-homologous end joining at telomere regulation of cell cycle
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