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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthesized peptide derived from human C/EBP- beta around the phosphorylation site of Threonine 235/188|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.5, with 50% glycerol|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Concentration is lot-specific and will vary from 0.5-0.6 mg/ml
Important transcriptional activator regulating the expression of genes involved in immune and inflammatory responses. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Functions in brown adipose tissue (BAT) differentiation. Regulates the transcriptional induction of peroxisome proliferator-activated receptor gamma (PPARG).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
AGP/EBP; C/EBP BETA; CCAAT/enhancer-binding protein beta; CEBPB; IL-6DBP; interleukin 6-dependent DNA-binding protein; interleukin-6-dependent-binding protein; LAP; LIP; liver-enriched transcriptional activator; liver-enriched transcriptional activator protein; nuclear factor NF-IL6; nuclear factor of interleukin 6; nuclear factor-IL6; nuclear protein Il6; SF-B; silencer factor B; TCF-5; TCF5; transcription factor 5
C/EBP-beta; C/EBPbeta; CRP2; IL-6DBP; IL6DBP; LAP; LIP; NF-IL6; NF-M; Nfil6; PP9092; TCF5
Nucleoside, nucleotide and nucleic acid metabolism mRNA transcription mRNA transcription regulation Immunity and defense Stress response Developmental processes Apoptosis Induction of apoptosis Inhibition of apoptosis Cell proliferation and differentiation